Arabinogalactan made of Siberian larch for sell export.
- stimulates the growth and development of beneficial gut microflora,
- improves peristalsis of the intestine,
- promotes regular elimination adsorbs and removes toxic substances, radionuclides and heavy metals lowers cholesterol and blood sugar,
- strengthens the immune system,
- regulates the appetite and is recommended in weight loss programs,
- protects from the negative effects of antibiotics, protects beneficial microflora of the intestine from the damaging effects of antibiotics,
- contributes to the enhancement of therapeutic effect with simultaneous use with drugs - prebiotics that contain live lactobacilli and bifidus bacteria.
Arabinogalactan in the pharmaceutical industry used in two ways:
1) As an auxiliary component
Having membranotropic properties and could prospectively be used as
"carriers" of drugs. Arabinogalactan allows to increase the solubility
sparingly soluble medicinal substances.
Arabinogalactan is a dietary Supplement that has a wide range of biological activity: gastroprotective, immunobiological properties. That is why the use of arabinogalactan as a carrier allows you to significantly expand the range of composite dosage forms and to improve their performance.
Arabinogalactan is also used as a binding nontoxic agent for tabletting
dosage forms with high strength. Arabinogalactan enhances the activity and effectiveness the release of various water-soluble drugs. It is used to improve absorbability other drugs with low bioavailability. In addition, having mefloquineuine and dispersing properties, arabinogalactan is used as an emulsifier stabilization of emulsions.
2) As a separate component
Arabinogalactan can be used as the main component of biologically active
additives used for prevention of cardiovascular, respiratory, infectious
disease; the normalization of the gastrointestinal tract; enhancing the immune system.
Studies have shown that arabinogalactan derived from Siberian larch, stimulates the activity of natural killer cells, cytokines and macrophages.
Natural killers – NK-lymphocytes, large lymphocytes with cytotoxicity against tumor cells and cells infected with viruses are one of the most important components of cellular innate immunity.
Cytokines regulate intercellular and intersystem interactions determine cell survival, stimulation or the suppression of their growth, differentiation, functional activity and apoptosis, as well as provide consistency the action of the immune, endocrine and nervous systems in normal conditions and in response to pathological effects.
Macrophages – cells capable of active capture and digestion of bacteria, debris dead cells and other foreign or toxic to the body particles.
Arabinogalactan supports the natural immune function, helps to increase the number of active immune cells and the production of antibodies based on the T-regulatory cells, T-suppressor cells to call appropriate immune response.
It stimulates the activity of natural killer cells (cytotoxic lymphocytes).
Arabinogalactan allows to induce circulation of a number of cytokines such as interferon gamma (Ifny), necrosis factor the tumor (TNF) and various interleukins (IL1, or IL6).
It also supports the functioning of macrophages, which are important elements in protective systems body.
It also increases the level of leukocytes. Studies have shown that arabinogalactan significantly increases the number circulating white blood cells. This is primarily related to an increase in the concentration of neutrophils.
Recent studies have shown that arabinogalactan causes the adaptive immune response to specific antigens.
In particular, a higher immune response immunoglobulin G vaccine was observed during 10 weeks after vaccination.
About Arabinogalactan (in Russian):
While Arabinogalactan has a huge impact on the health of the digestive system, he got even more attention for its ability to improve the health of our immune system.
Substances that promote a balanced response to stress, are called "adaptogens". Larch Arabinogalactan acts as an "adaptogenic" agent on our immune system, by identifying weaknesses and balancing to normal. Simply put - the immune system, which can work better in a balanced and appropriate way viewset weaknesses and eliminates voznikayuschie problems that adversely affect the operation of its protective functions.
Powder prebiotic, optionally fortified with Taxifolin, which is present in the arabinogalactan, but in small dosages (no more than 1-2%). Dihydroquercetin in this product is about 20% of arabinogalactan and clean around 78% -80%.
The appearance of white powder, with a very slight pine smell and sweet taste. It is 100% soluble in water and produces low solutions. Because of its excellent solubility and mild taste, the powder will satisfy even the smallest, for example, for children it can be mixed with juices.
Arabinogalactan is a highly branched polysaccharide consisting of galactinol the foundations of the side chains of the sugars arabinose and galactose. Larch arabinogalactan is an excellent source of fiber, and also approved as a food additive by the FDA.
Arabinogalactan is a natural immune stimulator, significantly activates the protective cells of the body. Is a source of soluble dietary fibers, necessary for the proper functioning of the immune system. Arabinogalactan has significant hepatoprotective and membranotropic properties. Due to the high concentration of the drug and ability to increase vascular permeability, arabinogalactan can be used as a therapeutic agent designed for the liver. Arabinogalactan is able to protect and strengthen cell membrane, and, consequently, reduce the osmotic swelling and disintegration of cells acidosis. In addition, Arabinogalactan can effectively prevent stress-induced liver damage, as well as to correct disorders of the liver structure, developing into a stage of anxiety stress reactions.
If taking the extract arabinogalactan and digidrokvertsetina has a significant impact on increasing beneficial bacteria and improving the intestinal microflora, in particular increasing anaerobes such as bifidobacteria and lactobacilli. Experimental studies have shown that larch arabinogalactan can stimulate natural cell-the"killer" (NK) cell cytotoxicity, enhance other functional aspects of the immune system, as well as to inhibit metastasis of cancer cells in the liver. The use in the preventive purposes - to create more flexible the immune system. Application in clinical medicine as a therapeutic agent in conditions associated with lowered immune function, reduction of NK activity or chronic viral infection.
Arabinogalactan also acts as a power source for beneficial bacteria. A term used to describe this effect is "prebiotic". The most well-known prebiotic substance "fructooligosaccharides" or "FOS". Arabinogalactan acts in the same way as fructooligosaccharides in the human body, promotes the growth of beneficial bacteria and short-chain fatty acids in the body, which is essential for maintaining normal functioning of the gastro-intestinal tract, as well as anti-inflammatory, gastroprotective, membranotropic activity. Arabinogalactan can be widely used in the production of functional foods. In fact, when we consume extract, arabinogalactan, we get positive effect in the microflora of our intestine, namely, its balance. In particular, this fiber increases good bacteria such as bifidobacteria and lactobacilli and at the same time reduces harmful bacteria. Friendly bacteria we need, as critical to the health of our digestive and immune systems, detoxification and hormone regulating the development and assimilation of nutrients.